RevolutionizingEmbryo Culture
EmbryoNest™ — The next generation substrate for IVF success. Engineered at the cellular level to mirror the natural embryonic microenvironment.
Why We BuiltOterus Bio
In their own words — the motivations and convictions that led our founders to reimagine the embryo culture environment.
"Oterus Bio began with the quiet grief my family experienced during our struggle to conceive. We were eventually successful, but the journey left us emotionally and financially devastated."
"In researching IVF, I discovered a heartbreaking reality: 62% of families drop out after 3–4 failed cycles. For many, the dream of parenthood is denied simply because they can no longer afford the gamble. This inequity is even more stark in minority communities; Black and Hispanic women are twice as likely to avoid IVF due to cost."
"Oterus was born from a passion to change this. We are developing technology to make IVF more predictable, efficient, and affordable. Our goal is to ensure that everyone has access to the most important experience of their lives. This isn't just a company; it is my mission to ensure no family has to walk away empty-handed."
Dr. Scott Rapoport
Co-Founder & Chief Executive Officer
"As a clinical embryologist, I have seen firsthand the heartbreak of failed IVF cycles. The uncomfortable truth is that over half of IVF cycles do not result in a healthy live birth. Why not? There are many reasons, but one critical factor is that embryo culturing occurs in an artificial environment. In vitro culturing often fails to replicate the nuances of the female reproductive tract, impeding the developmental and implantation competency of IVF-derived embryos."
"We can do better. At Oterus Bio, I bridge clinical embryology with human physiology to fix this "environment gap." By refining the microenvironment embryos experience in the lab, we ensure more embryos reach their full potential. My goal is to use my expertise to help families grow with fewer cycles and less emotional and financial cost. By improving the science of the culture, we are making the dream of a healthy live birth a reality for more families."

Dr. Lesley Blankenship-Williams
Co-Founder & Chief Scientific Officer
"I started this company because I've lived the heartbreak that so many IVF patients quietly carry. Across three IVF cycles, I retrieved 9–10 mature eggs each time, yet ended up with only three euploid embryos — including one cycle with none at all. Facing a roughly 10% euploid outcome was devastating, and it left me questioning how something so central to building a family could feel so unpredictable and out of our control. That question stayed with me."
"At the same time, I'm a bioengineer who has spent years developing biomaterials that mimic native biological environments. I've seen how profoundly cells respond when we recreate the cues they experience in the body, and I've long believed embryos deserve that same level of biological support. This company is where my personal IVF journey and my scientific training meet. By bringing biomimetic design into IVF, we aim to improve embryo quality and ease the emotional and financial burden for anyone fighting to build a family."
Stealth Mode
Co-Founder & Chief Technical Officer
EmbryoNest™
The Science of Biomimicry
EmbryoNest™ replicates the biochemical and structural complexity of the natural uterine environment, providing embryos with the precise conditions they need to thrive.
Murine Embryo Substrate Validation
In vitro testing with mouse embryo models
Biomimetic Substrate
EmbryoNest™ replicates the natural endometrial microenvironment, providing a scaffold that mirrors the biochemical and structural cues of the uterine lining.
Precision Engineering
Nanoscale surface architecture optimized through iterative in vitro testing to maximize trophectoderm adhesion and embryo competency.
Validated In Vitro
Extensive preclinical validation in-house, and externally using murine embryos demonstrates consistent outcomes in optimized embryo development vs standard culture conditions.
Biocompatible Materials
Formulated from FDA-recognized biocompatible polymers with a well-established safety profile in reproductive medicine applications.
Beyond Glass & Plastic
For decades, embryos have been cultured on surfaces they were never meant to encounter — glass and plastic — materials fundamentally foreign to the embryonic experience.
EmbryoNest™ replaces these unnatural surfaces with a substrate that closely mirrors the native tissue environment, giving embryos the biological context they need from the very start.
Learn MoreTeam & Advisory Board
World-class scientists, clinicians, and operators united by a shared mission to transform reproductive medicine through precision biomaterial science.
Dr. Scott Rapoport
Co-Founder & Chief Executive Officer
Expertise in Regenerative Medicine (Biomaterials) with 19+ years in industry startups. Experienced in leading large teams on complex products at the interface of biology and engineering. BSME (University of Florida); MEng (Bioengineering) UCSD & PhD (Marine Biology) UCSD-SIO. Postdoctoral training at the Children's Hospital of Philadelphia (CHOP).

Dr. Lesley Blankenship-Williams
Co-Founder & Chief Scientific Officer
An academician & embryologist focused on optimizing IVF outcomes through innovation, including developing a novel sperm cryo technique & a new platform for time-lapse incubators. T.S. certified in embryology & andrology by the ABB. BA in Pure Mathematics and Marine Biology from UC Santa Cruz; MS/PhD in Marine Biology from UC San Diego.
Stealth Mode
Co-Founder & Chief Technical Officer
A tissue engineering and regenerative medicine expert with over 18 years of experience on projects ranging from vascular tissue, stem cell, & lung tissue engineering. Led teams to successfully integrate, develop and design cell biomanufacturing, bioreactor, & biomaterial platforms. PhD & MS in Bioengineering from Georgia Tech, postdoc at Duke.

Dr. Klaus Wiemer
Scientific Advisor
30+ year IVF veteran. Former Laboratory Director at Poma Fertility, Genesis Fertility Centre, NW Center for Reproductive Science, Walter Reed Army Medical Center, and NW Center for Infertility & Reproductive Endocrinology.

Alease Barnes
Operations Advisor
VP of Embryology Science Education & Business Development, Gattaca Genomics. CEO & Founder, ReproMedia Consulting. Instructor, ARTLAB IVF Training Center.

David Stern
Business Advisor
Current CEO, Kindbody. Former CEO of Boston IVF and Symbiomix Therapeutics. Sr. VP & Head of Global Fertility Franchise Business, Merck. Former EVP Endocrinology, EMD Serono.

Professor Barry Behr
Scientific Advisor
Professor of Obstetrics & Gynecology (Reproductive Endocrinology & Infertility), Emeritus, Stanford University. IVF Laboratory Director. Founder: Auxogyn, Blastogen, & IVIGen.
Science, Stories &
Publications
Coming Soon
We're compiling our publications, media, and scientific resources. Check back soon — or reach out directly if you'd like to be notified when new material is available.
Connect With Oterus Bio
Whether you're a researcher, clinician, or industry partner, we welcome the conversation.
EmbryoNest™ is not currently FDA-cleared or approved for clinical use. We are actively pursuing regulatory pathways. In the meantime, we welcome Research Use Only (RUO) engagements with qualified research institutions and industry partners.
Engagements
RUO & Partnership Inquiries
Interested in an RUO engagement or research collaboration with EmbryoNest™? Our team will walk you through current availability, research partnership structures, and next steps.
Information
General Questions
Have a question about our science, company, or partnership opportunities? We'd love to hear from you and will respond within one business day.
